Johnsonville is a city in Florence County, South Carolina, United States. The population was 1,480 at the 2010 census. It is part of the Florenc…Johnsonville is a city in Florence County, South Carolina, United States. The population was 1,480 at the 2010 census. It is part of the Florence Metropolitan Statistical Area. The city was founded in 1913 west of the spot of the former Witherspoon's Ferry on Lynches River, where General Francis Marion received his commission for the Revolutionary War.
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