Fluorouracil - Wikipedia
WEBFluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.
Fluorouracil - StatPearls - NCBI Bookshelf
WEBNov 24, 2022 · Continuing Education Activity. 5-Fluorouracil (5-FU) is a medication used to treat various neoplasms. It is in the chemotherapy class of drugs. This activity outlines the indications, mechanism of action, and contraindications for 5-FU as a valuable agent in treating various visceral and dermatologic malignancies.
5-氟尿嘧啶 - 维基百科，自由的百科全书
WEB化疗药5-Fu於1956年取得專利，1962年開始用於醫療，被列為 世界衛生組織基本藥物 [1] 。. 用于治疗肿瘤已超過50余年，可通过多种途径发挥作用，其中最主要的作用方式是作为 胸苷酸合成酶抑制剂 ，阻断 DNA复制 的必需原料—— 胸腺嘧啶 的合成。. 胸苷酸合成 使 ...
5-Fluorouracil: mechanisms of action and clinical strategies
WEBMay 1, 2003 · Key Points. The fluoropyrimidine 5-fluorouracil (5-FU) is an antimetabolite drug that is widely used for the treatment of cancer, particularly for colorectal cancer. 5-FU exerts its...
Fluorouracil (5FU) | Cancer information | Cancer Research UK
WEBJul 26, 2023 · Fluorouracil (5FU) is a chemotherapy drug. It is a treatment for many different types of cancer. Find out how you have it, side effects and other important information.
5FU Chemo: How It Works, Delivery, Side Effects, and More
WEBJul 14, 2022 · Fluorouracil (5FU) is a type of chemotherapy drug. It’s typically used in combination with other cancer drugs to treat several different types of cancer, including: breast cancer. colorectal ...
5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs
WEBSep 17, 2010 · 5-Fluorouracil (5-FU) is a key anticancer drug that for its broad antitumor activity, as well as for its synergism with other anticancer drugs, has been used to treat various types of malignancies. In chemotherapeutic regimens, 5-FU has been combined with oxaliplatin, irinotecan and other drugs as a continuous intravenous infusion.
5-Fluorouracil: A Narrative Review on the Role of Regulatory …
WEBApr 19, 2021 · Catabolic and Anabolic Way of 5-Fluorouracil Transformation. 5-FU is a uracil analog with a fluorine atom at the C-5 position. After intravenous administration of 5-FU, this medication can rapidly enter target cells …
Fluorouracil Injection - NCI - National Cancer Institute
WEBUse in Cancer. Fluorouracil injection is approved to treat: Breast cancer. Colorectal cancer. Gastric (stomach) cancer. Pancreatic cancer. Fluorouracil is also called 5-FU. Fluorouracil is also being studied in the treatment of other conditions and types of cancer. Fluorouracil is also available in a topical form.
Fluorouracil - Chemocare
WEBSide effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat. Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded.
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