Doxofylline: Uses, Interactions, Mechanism of Action - DrugBank …
WebDoxofylline is a methylxanthine bronchodilator with potent bronchodilator activity comparable to that of theophylline. In animal studies, doxofylline demonstrated to attenuate bronchoconstriction, inflammatory actions and the release of thromboxane A2 (TXA2) when challenged with platelet-activating factor 9.
Doxofylline - Wikipedia
WebDoxofylline (also known as doxophylline) is a phosphodiesterase inhibiting bronchodilator used in the treatment of chronic respiratory diseases such as asthma and COPD. Like theophylline, it is a xanthine derivative.
Doxofylline - Uses, Dosage, Side Effects, Price, Composition - Practo
WebSep 28, 2021 · Doxofylline is a bronchodilator, that helps relax the smooth muscles of the airways in your lungs. This medicine is available on prescription as a tablet, suspension, syrup and injection forms. Doxofylline may show some side effects like vomiting, headache, nausea, and an upset stomach.
Doxofylline - Uses, Side Effects, Substitutes, Composition
WebDoxofylline is used for Asthma, Chronic Obstructive Pulmonary Disorder (Copd) etc. Know Doxofylline uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate.com
Doxofylline - an overview | ScienceDirect Topics
WebDoxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as theophylline and the evidence supporting the effects of doxofylline in the treatment of lung diseases is discussed.
Doxofylline: Indication, Dosage, Side Effect, Precaution - MIMS
WebGeneric Medicine Info. Indications and Dosage. Oral. Bronchial asthma, Chronic obstructive pulmonary disease. Adult: Recommended dose: 400 mg bid-tid. Max: 1,200 mg daily. Elderly: Reduce dose to 200 mg bid-tid. Child: As syr: …
Doxofylline is not just another theophylline! - PMC
WebDec 5, 2017 · Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.
Efficacy and safety profile of doxofylline compared to …
WebAug 3, 2019 · Results. Data obtained from 696 asthmatic patients were extracted from 4 randomized controlled trials published between 2015 and 2018. Doxofylline was significantly ( P < 0.05) more effective than theophylline in reducing the daily asthma events (mean difference − 0.14, 95%CI -0.27 – 0.00) and risk of AEs (relative risk 0.76, 95%CI …
The effect of doxofylline in asthma and COPD - Respiratory …
WebFeb 18, 2020 · Doxofylline is a newer generation xanthine with both bronchodilating and anti-inflammatory activities and for this reason it has been called “novofylline”. It differs substantially from theophylline at the pharmacological level. Clinical studies have shown substantial differences between doxofylline and theophylline.
Efficacy and safety profile of doxofylline compared to …
WebAug 3, 2019 · Doxofylline is an effective and safe methylxanthine for the treatment of asthma, with an efficacy/safety profile greater than that of theophylline. Trial registration. Meta-analysis registration: CRD42019119849. Background.
Skip to content