Interferon - Wikipedia
WEBInterferons (IFNs, / ˌ ɪ n t ər ˈ f ɪər ɒ n / IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.
Interferon type I - Wikipedia
WEBThe type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses.
Mechanisms of type-I- and type-II-interferon-mediated signalling …
WEBMay 1, 2005 · Interferons (IFNs) are widely expressed cytokines that have potent antiviral and growth-inhibitory effects. These cytokines are the first line of defence against viral infections and have...
IFNγ: signalling, epigenetics and roles in immunity ... - Nature
WEBJun 19, 2018 · IFNγ is a cytokine that is primarily produced by cells of the immune system, including innate-like lymphocyte populations, such as natural killer (NK) cells and innate lymphoid cells (ILCs), and...
Viruses and interferon: a fight for supremacy - Nature
WEBSep 1, 2002 · Interferons (IFNs) — the body's first line of antiviral defence — are cytokines that are secreted by host cells in response to virus infection. By inducing the expression of hundreds of...
The Type I Interferons: Basic Concepts and Clinical Relevance in …
WEBJan 1, 2016 · The interferons (IFN)s are a family of cytokines with antiviral, antiproliferative, and antitumor activities, as well as immunomodulatory effects on the innate and adaptive immune responses ( Lengyel, 1982; Pestka et al., 1987 ).
Interferon - StatPearls - NCBI Bookshelf
WEBJul 10, 2023 · Interferons are currently used clinically to treat viral infections such as hepatitis C, cancers including non-Hodgkin’s lymphoma, and autoimmune diseases such as multiple sclerosis. This activity outlines the different types of interferons, namely interferon alpha, beta, and gamma.
11.4B: Interferons - Biology LibreTexts
WEBDec 24, 2022 · Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. IFNs belong to the large class of glycoproteins known as cytokines. Interferons are named after their ability to “interfere” with viral replication within host cells.
Interferons Overview | Thermo Fisher Scientific - US
WEBInterferons Overview. What is an interferon? Interferon (IFN) proteins are a family of cytokines secreted by host cells to modulate the immune response. As the first class of cytokines discovered, they were named “interferon” due to the protein’s ability to interfere with viral replication.
Interferon gamma - Wikipedia
WEBInterferon gamma - Wikipedia. Contents. hide. (Top) Function. Structure. Receptor binding. Signaling. JAK-STAT pathway. Other signaling pathways. Biological activity. Activity in granuloma formation. Activity during pregnancy. Production. Therapeutic use. Potential use in immunotherapy. Cancer immunotherapy. Involvement in antitumor immunity.
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