Pyrrolidine - Wikipedia
WebPyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH 2) 4 NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most organic solvents.
Pyrrolidine | C4H9N | CID 31268 - PubChem
WebPyrrolidine is a cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family. It is a saturated organic heteromonocyclic parent, a member of pyrrolidines and an azacycloalkane. It is a conjugate base of a pyrrolidinium ion.
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel ...
WebAug 10, 2021 · In this review, we report bioactive molecules with target selectivity characterized by the pyrrolidine ring and its derivatives, including pyrrolizines, pyrrolidine-2-one, pyrrolidine-2,5-diones and prolinol described in …
Recent insights about pyrrolidine core skeletons in pharmacology
WebSep 6, 2023 · This review focuses on the current progress in pyrrolidine derivatives, which show multiple pharmacological activities and functions in the treatment of several health disorders. Pyrrolidine-based therapeutic candidates are currently used in the therapy of some diseases.
Pyrrolidine - NIST Chemistry WebBook
WebC p,liquid: Constant pressure heat capacity of liquid: P c: Critical pressure: S° liquid Entropy of liquid at standard conditions: T boil: Boiling point: T c: Critical temperature: T fus: Fusion (melting) point
Pyrrolidine - NIST Chemistry WebBook
WebIUPAC Standard InChI: InChI=1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2 Copy IUPAC Standard InChIKey: RWRDLPDLKQPQOW-UHFFFAOYSA-N Copy CAS Registry Number: 123-75-1 Chemical ...
Pyrrolidine - an overview | ScienceDirect Topics
WebChemical Properties. Pyrrolidine being a good nucleophile easily undergoes electrophilic substitution reactions with different electrophiles such alkyl halides and acyl halides, and forms N -substituted pyrrolidines. N -Alkylpyrrolidine on further reaction with alkyl halide provided quaternary salts.
Pyrrolidine | C4H9N | ChemSpider
WebPyrrolidine. Molecular Formula C 4 H 9 N; Average mass 71.121 Da; Monoisotopic mass 71.073502 Da; ChemSpider ID 29008
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel ...
WebAug 10, 2021 · Abstract. The five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases. The great interest in this saturated scaffold is enhanced by (1) the possibility to efficiently explore the pharmacophore space due to sp 3 -hybridization, (2) …
Therapeutic potential of pyrrole and pyrrolidine analogs: an …
WebJan 25, 2022 · Pyrrolidine (saturated pyrrole) analog; telaprevir is an antiviral drug, peptidomimetic used in combination therapy to treat chronic Hepatitis C Virus (HCV) infection. This drug inhibits NS3/4A, a serine protease encoded by HCV genotype 1 and SARS-CoV-2 3CL proteases.
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