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  2. sufuorg.com
    https://sufuorg.com

    Home | Society of Urodynamics, Female Pelvic Medicine

    See results only from sufuorg.com
  3. sufuorg.com
    https://sufuorg.com/resources/patients.aspx

    For Patients | Society of Urodynamics, Female Pelvic Medicine ...

  4. GeneCards
    https://www.genecards.org/.../carddisp.p…

    SUFU Gene - GeneCards | SUFU Protein | SUFU Antibody

    WEBApr 3, 2024 · SUFU (SUFU Negative Regulator Of Hedgehog Signaling) is a Protein Coding gene. Diseases associated with SUFU include Joubert Syndrome 32 and Basal Cell Nevus Syndrome 2. Among its related …

  5. Nature
    https://www.nature.com/articles/s41419-021-03487-0

    Positive feedback of SuFu negating protein 1 on Hedgehog

  6. Nature
    https://www.nature.com/articles/s41467-01…

    Itch/β-arrestin2-dependent non-proteolytic …

    WEBMar 7, 2018 · Suppressor of Fused (SuFu), a tumour suppressor mutated in medulloblastoma, is a central player of Hh signalling, a pathway crucial for development and deregulated in cancer. Although...

  8. Pediatric Neurology
    https://www.pedneur.com/article/S0887-8994(23)00404-6/fulltext

    Macrocephaly? Do not Forget SUFU - Pediatric Neurology

  9. Nature
    https://www.nature.com/articles/s41418-022-01073-1

    Inhibition of the transcription factor ZNF281 by SUFU to ... - Nature

  10. People also ask
    What does Sufu stand for?
    The mission of the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) is to optimize the care of women, men, and children with lower urinary tract dysfunction and/or pelvic floor disorders through education, research and involvement in health care policy.

    Home | Society of Urodynamics, Female Pelvic Medicine & Urogenital

    sufuorg.com
    Why is Sufu important?
    SuFu, a PEST-domain protein, serves as a key negative regulator of Hh signaling by preventing the nuclear accumulation of Gli transcriptional factors. It plays an essential role in embryonic development, as knocking out the SuFu gene results in early embryonic lethality at gestation with neural tube defects 15.

    Positive feedback of SuFu negating protein 1 on Hedgehog ... - Nature

    nature.com
    What is SUFU in Drosophila?
    Suppressor of fused (Sufu/SUFU) is one of the key components of the Hh pathway and acts as a negative regulator both in vertebrate and invertebrate to ensure appropriate signal output [ 5, 6 ]. In Drosophila, Sufu forms a complex with Costal2 (Cos2) and Fused (Fu) to block Ci nuclear import [ 2, 7, 8 ].

    Inhibition of the transcription factor ZNF281 by SUFU to ... - Nature

    nature.com
    What diseases are associated with Sufu?
    Diseases associated with SUFU include Joubert Syndrome 32 and Basal Cell Nevus Syndrome 2 . Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Signaling by Hedgehog . Gene Ontology (GO) annotations related to this gene include protein kinase binding and obsolete signal transducer activity .

    SUFU Gene - GeneCards | SUFU Protein | SUFU Antibody

    genecards.org
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  11. PNAS
    https://www.pnas.org/doi/10.1073/pnas.20…

    Sufu negatively regulates both initiations of …

    WEBJul 6, 2021 · Here, we report that Sufu inhibits centrosome duplication via facilitating CP110 phosphorylation and suppresses DNA replication via promoting intranuclear Cdt1 degradation and expelling prereplication …

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