Tetrodotoxin - Wikipedia
WEBTetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin.
Tetrodotoxin: Biotoxin | NIOSH | CDC
WEBNIOSH, CDC 2003. Tetrodotoxin is an extremely potent poison (toxin) found mainly in the liver and sex organs (gonads) of some fish, such as puffer fish, globefish, and toadfish (order Tetraodontiformes) and in some amphibian, octopus, and shellfish species.
Tetrodotoxin: Uses, Interactions, Mechanism of Action
WEBGeneric Name. Tetrodotoxin. DrugBank Accession Number. DB05232. Background. An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.
From Poison to Promise: The Evolution of Tetrodotoxin and Its …
WEBJul 24, 2021 · Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria. However, determining its origin, ecosystem roles, and biomedical applications has challenged researchers for decades.
Tetrodotoxin | SpringerLink
WEBJun 25, 2017 · Tetrodotoxin (TTX) with a toxicity more than 1000 times greater than sodium cyanide (median lethal dose approximately 10 μg/kg versus 10 mg/kg for sodium cyanide) is one of the most potent marine poisons known [1–3]. It …
Tetrodotoxin - American Chemical Society
WEBApr 6, 2010 · MOTW update: September 27, 2021. Tetrodotoxin is an extremely toxic natural substance—the poisonous principle in pufferfish and other marine animals. Tetrodotoxin, a nerve blocker, has been tested as a local anesthetic, but its concentration range must be limited to prevent it from becoming systemically toxic.
Tetrodotoxin - Wikiwand
WEBTetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish, it is found in several other animals.
WEBanhydro-Tetrodotoxin, 9-epiTetrodotoxin, and 9-epi lactone-Tetrodotoxin. Tetrodotoxin (TTX, 1) is one of the most potent neurotoxins with a complex structure and analgesic effects.
Confirmation and Distribution of Tetrodotoxin for the First Time …
WEBJun 25, 2014 · Tetrodotoxin is a low molecular weight compound that acts by blocking voltage-gated sodium channels, inducing paralysis. However, the origins and ecological functions of TTX in most taxa remain mysterious.
Marine Drugs | Free Full-Text | Tetrodotoxin, an Extremely Potent ...
WEBOct 19, 2015 · Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria …
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