Chondrocyte - Wikipedia
WEBChondrocytes ( / ˈkɒndrəsaɪt, - droʊ -/, [1] from Greek χόνδρος, chondros = cartilage + κύτος, kytos = cell) are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.
Chondrocytes: anatomy and function | Kenhub
WEBMar 19, 2024 · Anatomy, histology and definition of cartilage. Chondrocytes produce collagen and the extracellular matrix. They are found in the avascular tissue known as cartilage . The extracellular matrix that is produced by the chondrocytes is important in the maintenance of cartilaginous tissue.
The life cycle of chondrocytes in the developing skeleton
WEBNov 8, 2001 · Chondrocytes exhibit a life cycle of proliferation, differentiation, maturation, and apoptosis; the rate of each of these processes is dependent on temporal and spatial cues within the body. Identifying and characterizing these cues will reveal the molecular basis of cartilage form and function.
Frontiers | Molecular Mechanisms of Chondrocyte Proliferation …
WEBMay 28, 2021 · The process of chondrocyte proliferation and differentiation is affected by key factors (such as Sox9, Runx2, BMPs) and cell signals (such as Wnt, TGF-β, FGF, Ihh, and Nocth), thereby promoting the synthesis of ECM and expressing the characteristics and functions of chondrocytes.
Chondrocyte | anatomy | Britannica
WEBanatomy. Learn about this topic in these articles: component of cartilage. In connective tissue: Cartilage. The cells of cartilage, called chondrocytes, are isolated in small lacunae within the matrix. Although cartilage is avascular, gaseous metabolites and nutrients can diffuse through the aqueous phase of the gel-like matrix to reach the cells.
Cartilage and Chondrocytes | Musculoskeletal Key
WEBJul 3, 2016 · Adult articular chondrocytes are nonmitotic cells that survive at low oxygen tension in the absence of a vascular supply. In response to trauma or inflammation, the metabolic activity of the chondrocyte is increased in response to catabolic and anabolic factors that regulate remodeling of the ECM.
The Origin and Fate of Chondrocytes: Cell Plasticity in …
WEBHere, we discuss the origin of chondrocytes, their destiny, and their plasticity in relationship to bone growth, articulation, and formation of the trabeculae. We also consider these processes from a biological, clinical, and evolutionary perspective.
Frontiers | Chondrocyte Aging: The Molecular Determinants and ...
WEBJul 14, 2021 · Hallmarks of chondrocyte aging inflammation, oxidative stress (excess production and accumulation of ROS and the related dysfunctioning of cellular components) and senescence are fundamental events that is associated with the onset of cellular aging and aging-associated degenerative disorders.
Chondrocytes: Methods and Protocols | SpringerLink
WEBThis detailed book collects a variety of methods from investigators at the forefront of chondrocyte biology and pathology research that they have tailored for their research projects in order to tackle the unique properties and challenges of the chondrocyte and those of its tissue matrix.
JCI - Regulation of chondrogenesis and chondrocyte …
WEBFeb 1, 2008 · Chondrogenesis is a process that is important for the creation of chondrocytes both during embryogenesis as well as in adult life (e.g., during skeletal tissue repair). The process begins with the aggregation …
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