brefeldin A | C16H24O4 | CID 5287620 - PubChem
WEBDecumbin. 20350-15-6. Synergisidin. View More... Molecular Weight. 280.36 g/mol. Computed by PubChem 2.2 (PubChem release 2021.10.14) Dates. Create: 2005-11-29. Modify: 2024-04-16. Description. Brefeldin A is a metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. It has a role as a Penicillium metabolite.
Decumbin, a New Compound from a Species of Penicillium
WEBA new class of antimicrobial molecules derived from kefir, effective against Pseudomonas aeruginosa and methicillin resistant Staphylococcus aureus (MRSA) strains. Article Open access 15 October...
Biological effects of the antibiotic brefeldin A (decumbin, cyanein ...
WEBBiological effects of the antibiotic brefeldin A (decumbin, cyanein, ascotoxin, synergisidin): a retrospective. Folia Microbiol (Praha). 1992;37 (1):3-11. doi: 10.1007/BF02814572. Author. V Betina 1. Affiliation. 1 Department of Microbiology, Biochemistry and Biology, Faculty of Chemical Technology, Slovak Technical University, Bratislava.
Brefeldin A, a cytotoxin produced by - Oxford Academic
WEBSep 1, 2002 · Brefeldin A, also named decumbin, cyanein, ascotoxin and sinergisidin , is a 16-membered macrolide antibiotic which had previously been isolated from a number of fungal genera: Alternaria, Ascochyta, Penicillium, Curvularia, Cercospora, and Phyllosticta.
Biological effects of the antibiotic brefeldin A (Decumbin, cyanein ...
WEBAbstract. Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal growth and ...
Decumbin, a New Compound from a Species of Penicillium
WEBDecumbin, a New Compound from a Species of Penicillium. AN organism isolated during a microbiological study of corn spoiled in storage produced an aroma reminiscent of exaltone and crystalline bodies in artificial culture.
Ascotoxin (Decumbin), a Metabolite of Ascochyta imperfecta …
WEBMar 1, 1970 · Abstract. From the mycelium of Ascochyta imperfecta decumbin, C 16 H 24 O 4, mp 203°C, was obtained in one percent yield.. The absolute structure of decumbin was presented as [II] by the following evidences: The configuration about C 4 was determined as (S) by the benzoate rule on the tetrahydromonoketone (21). The hydroxyl at C 7 is α, because tetrahydrodecumbin (23) showed no ...
WEBBrefeldin A (as decumbin) has been found to inhibit wheat germination (Singleton et al. 1958) and (as cyanein) the growth of roots in Allium cepa (Betina et al. 1%3). When its effects on the mitotic cycle in root tips of.
Identification of novel antiviral of fungus-derived brefeldin A …
WEBOct 26, 2017 · We identified brefeldin A as a novel antiviral agent against dengue viruses. The inhibitory effect of brefeldin A was confirmed by virus titer and immunofluorescence assay. Brefeldin A inhibited dengue viruses regardless of serotypes and other related viruses including Zika virus and Japanese encephalitis virus.
Decumbin, a new compound from a species of Penicillium
WEBDecumbin, a new compound from a species of Penicillium. Nature. 1958 Apr 12;181 (4615):1072-3. doi: 10.1038/1811072a0. Authors. V L SINGLETON , N BOHONOS , A J …
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