Digitoxin - Wikipedia
WebDigitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting.
Digitoxin: Uses, Interactions, Mechanism of Action | DrugBank …
WebDigitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.
Digitoxin and its analogs as novel cancer therapeutics - PMC
WebApr 5, 2012 · However, digitoxin is perhaps one of the most promising anti-cancer CGs since it shows significant anticancer effect against several types of cancer including lung cancer, pancreatic cancer, leukemia, and breast cancer, all at therapeutic concentrations (see Table Table1) 1) [18,31,58,68,72].
Digitoxin | pharmacology | Britannica
Webdigitoxin. pharmacology. Learn about this topic in these articles: effect on cardiovascular system. In cardiovascular drug: Contractions. …used therapeutically are digoxin and digitoxin. Read More. plant source. In steroid: Cardiac glycosides and aglycones. in foxglove ( Digitalis ): digitoxin, gitoxin, and digoxin.
Treatment with digoxin: Initial dosing, monitoring, and dose ... - UpToDate
WebAug 21, 2023 · While two cardiac glycosides (digoxin and digitoxin) were previously used, digitoxin has not been widely available since the 1980s. As digoxin is now the only cardiac glycoside available in most countries, the method of initiating therapy with digoxin for patients with atrial fibrillation is presented here.
Simple and safe digitoxin dosing in heart failure based on data …
WebApr 22, 2023 · The new digitoxin dosing score advises, whether a patient should be started with a low dose of 0.05 mg digitoxin o.d. The digitoxin dosing score can easily be obtained in clinical routine and enables simple and safe initial digitoxin dosing in …
Digitoxin - an overview | ScienceDirect Topics
WebIt is cardiotonic and is used to increase cardiac contractility in the treatment of heart failure. The steroid nucleus and lactone ring are necessary for activity; other constituents influence pharmacokinetic variables. Its oral LD 50 is 60 mg/kg in guinea pigs and 0.18 mg/kg in cats.
Digitoxin - Side Effects, Uses, Dosage, Overdose, Pregnancy
WebNov 8, 2013 · Atrial Flutter. Cardiac Output, Low. Shock, Cardiogenic. Tachycardia, Supraventricular. Digitoxin is used in the prevention of: Heart Failure. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Digitoxin Brand Names. Digitoxin may be found in some form under the following brand names: …
Digitoxin - an overview | ScienceDirect Topics
WebDigitalis glycoside digoxin and digitoxin are potent cardiotonics found in Digitalis spp. (foxglove). Digoxin is available in tablet form and is prescribed to persons with congestive heart failure and atrial fibrillation ( Beyer et al ., 2009b; Bandara et al ., 2010 ).
Digitalis Toxicity - StatPearls - NCBI Bookshelf
WebMay 1, 2023 · Digoxin is a well-known cardiac glycoside and one of the oldest drugs used today in cardiovascular medicine. It has wide-ranging beneficial effects and continues to play an important role in the contemporary management of appropriately selected patients with heart failure and atrial fibrillation.
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