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  1. WEBFeb 1, 2008 · Drugs are often chemically derivatized prior to their GC-MS analysis for the following reasons: (a) to bring the analytes to the …

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    • Studies of drug%20derivatization
    • WEBAug 29, 2023 · Derivatization is generally necessary in the analysis by GC of compounds that exhibit low volatility, have poor thermal stability, contain “active” groups that can lead to loss of sample to intermolecular …

    • Derivatization procedures and their analytical …

      WEBOct 20, 2020 · Derivatization, or chemical structure modification, is often used in bioanalysis performed by liquid chromatography technique in order to enhance detectability or to improve the chromatographic performance …

    • WEBSep 13, 2018 · The derivatization is typically done to change the analyte properties for a better separation and also for enhancing the method sensitivity. In GC/MS, derivatization may improve the capability of …