Fumaric acid - Wikipedia
WEBFumaric acid has been used as a food acidulant since 1946. It is approved for use as a food additive in the EU, [6] USA [7] and Australia and New Zealand. [8] As a food additive, it is used as an acidity regulator and can be denoted by the E number E297. It is generally used in beverages and baking powders for which requirements are placed on ...
Fumarate | C4H2O4-2 | CID 5460307 - PubChem
WEBFumarate | C4H2O4-2 | CID 5460307 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Fumarate Definition & Meaning - Merriam-Webster
WEBApr 2, 2024 · noun. fu· ma· rate ˈfyü-mə-ˌrāt. : a salt or ester of fumaric acid. Examples of fumarate in a Sentence. Recent Examples on the Web This formula includes: Capsimax powder Chromium picolinate Caffeine Nopal L-carnitine fumarate Read on below to learn about the impact that each of these ingredients has on the body.
Fumarate suppresses B-cell activation and function through direct ...
WEBJun 16, 2022 · Mechanistically, fumarate is a covalent inhibitor of tyrosine kinase LYN, a key component of the BCR signaling pathway. Fumarate can directly succinate LYN at C381 and abrogate LYN activity,...
Fumarate: Multiple functions of a simple metabolite - PubMed
WEBAlthough much is now known about fumarate metabolism, our knowledge of some aspects of its biological function remain far from comprehensive. In this short review we begin with an introductory overview of the role of fumarate in both plant and non-plant systems.
Fumaric Acid | C4H4O4 | CID 444972 - PubChem
WEBFumarate is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate from food. It is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. Fumarate is then converted by the enzyme fumarase (fumarate hydratase) to malate.
Emerging therapeutic applications for fumarates - PMC
WEBAbstract. Fumarates are successfully used for the treatment of psoriasis and multiple sclerosis. Their antioxidative, immunomodulatory and neuroprotective properties make fumarates attractive therapeutic candidates for other pathologies. The exact working mechanisms of fumarates are, however, not fully understood.
Fumarate: Multiple functions of a simple metabolite
WEBJun 1, 2011 · Biological function of fumarate metabolism remains far from comprehensive. Here the relative importance of fumarate is discussed. The involvement of fumarate in pH regulation and stomatal movement is shown. Engineering the fumarate metabolism may provide opportunities to improve plant growth.
Fumarate is a terminal electron acceptor in the mammalian …
WEBDec 12, 2021 · Science. Author manuscript; available in PMC 2022 Jun 3. Published in final edited form as: Science. 2021 Dec 3; 374 (6572): 1227–1237. Published online 2021 Dec 2. doi: 10.1126/science.abi7495. PMCID: PMC8803114. NIHMSID: NIHMS1771049. PMID: 34855504. Fumarate is a terminal electron acceptor in the mammalian electron …
Mitochondrial molecule controls inflammation - Nature
WEB08 March 2023. Mitochondrial molecule controls inflammation. Cellular organelles called mitochondria contain their own DNA and RNA. The molecule fumarate has now been found to trigger the release...
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