1. The effect of fuscin on the mitochondrial oxidation of pyruvate plus malate, of succinate and of ascorbate plus tetramethyl-p-phenylenediamine (TMPD) and on the redox changes of succinate-reducible cytochromes b and c was investigated using tightly-coupled

Lipofuscins, also known as age-pigments, have three defining characteristics: (1) they consist of intracellular secondary lysosomes; (2) they have a yellow autofluorescent emission when excited by near ultraviolet or blue light; and (3) they accumulate

Inflammation is a cellular response to factors that challenge the homeostasis of cells and tissues. Cell-associated and soluble pattern-recognition receptors, e.g. Toll-like receptors, inflammasome receptors, and complement components initiate complex