Imidazole - Wikipedia
WebImidazole (ImH) is an organic compound with the formula C 3 N 2 H 4. It is a white or colourless solid that is soluble in water, producing a mildly alkaline solution. In chemistry, it is an aromatic heterocycle , classified as a diazole , and has non-adjacent nitrogen atoms in meta-substitution .
Imidazole | C3H4N2 | CID 795 - PubChem
WebImidazole is used as a Karl Fischer reagent in analytical chemistry and a reagent in synthetic organic chemistry. It is also used in the biological control of pests, especially fabric-feeding insects, often in combination with dl-p-fluorophenylalanine .
Imidazole: Synthesis, Functionalization and Physicochemical …
WebJan 13, 2023 · Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature provides much information about the synthesis, functionalization, physicochemical characteristics and biological role of imidazole.
Imidazole | Amino Acids, Heterocycles & Bases | Britannica
Webimidazole, any of a class of organic compounds of the heterocyclic series characterized by a ring structure composed of three carbon atoms and two nitrogen atoms at nonadjacent positions. The simplest member of the imidazole family is imidazole itself, a compound with molecular formula C 3 H 4 N 2.
Imidazole - an overview | ScienceDirect Topics
Web4.02.1 Introduction. Imidazole 1 is the universally used trivial name for 1,3-azole. Earlier given names were glyoxaline and iminazole. The importance of this aromatic ring system is reflected by its presence in naturally occurring histidine, histamine and the purines, and in several classes of pharmaceuticals.
Imidazole as a Promising Medicinal Scaffold: Current Status and …
WebJul 29, 2021 · Abstract. Various imidazole-containing compounds have been tested for their medical usefulness in clinical trials for several disease conditions. The rapid expansion of imidazole-based medicinal chemistry suggests the promising and potential therapeutic values of imidazole-derived compounds for treating incurable diseases.
Imidazole | Formula, Properties & Application
WebImidazole. Explore the properties, synthesis, and applications of Imidazole in biology, medicine, and industry, with a focus on safety and environmental considerations.
Synthesis and therapeutic potential of imidazole containing …
WebFeb 18, 2021 · Abstract. Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen.
Imidazole: Uses, Interactions, Mechanism of Action | DrugBank …
WebJun 13, 2005 · Alpha,alpha-trehalose-phosphate synthase (udp-forming) activity. Specific Function. Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.
Imidazole - an overview | ScienceDirect Topics
WebThe commonly known imidazole compounds are clotrimazole, ketoconazole, and miconazole. Azole derivatives (e.g., fluconazole, itraconazle, voriconazole, ravuconazole, posoconazole) with 1, 2, 4-triazole ring in place of imidazole have better pharmacokinetics profile with better fungicidal activity and lower toxicity.
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