Langerhans cell - Wikipedia
WEBA Langerhans cell ( LC) is a tissue-resident macrophage of the skin [2] once thought to be a resident dendritic cell. [3] These cells contain organelles called Birbeck granules. They are present in all layers of the epidermis and are most prominent in the stratum spinosum. [4]
Langerhans Cell Histiocytosis Treatment - NCI - National Cancer Institute
WEBMar 29, 2024 · Langerhans Cell Histiocytosis (LCH) treatment depends on where it is found in the body and whether the LCH is low or high risk. Treatment can include chemotherapy, surgery, radiation therapy, photodynamic therapy, immunotherapy, and targeted therapy. Learn more in this expert-reviewed summary.
Langerhans Cell Histiocytosis - Cleveland Clinic
WEBDec 26, 2023 · Langerhans cell histiocytosis (LCH) is a rare disorder that primarily affects babies and children. The disorder occurs when immune system cells called Langerhans cells build up in your child’s body. Langerhans cells are a type of white blood cell that helps your child’s immune system fight infection. Your child has Langerhans cells ...
Langerhans Cell Histiocytosis (LCH): Symptoms, Causes, Treatment - WebMD
WEBSep 21, 2023 · Cancer Guide. What Is Langerhans Cell Histiocytosis? Medically Reviewed by Melinda Ratini, MS, DO on September 21, 2023. Written by Sally Shepard. …
Langerhans Cell Histiocytosis - Hematology and Oncology
WEBLangerhans cell histiocytosis (LCH) is a proliferation of dendritic mononuclear cells with infiltration into organs locally or diffusely. Most cases occur in children. Manifestations may include lung infiltrates; bone lesions; rashes; and …
Langerhans cell histiocytosis: MedlinePlus Genetics
WEBLangerhans cell histiocytosis is a disorder in which excess immune system cells called Langerhans cells build up in the body. Langerhans cells, which help regulate the immune system, are normally found throughout the body, especially in the skin, lymph nodes, spleen, lungs, liver, and bone marrow.
Langerhans cell histiocytosis - Wikipedia
WEBPathophysiology. Diagnosis. Treatment. Prognosis. Prevalence. Culture. Nomenclature. References. External links. Langerhans cell histiocytosis ( LCH) is an abnormal clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes .
Langerhans Cell Histiocytosis Treatment (PDQ®) - NCI
WEBApr 11, 2024 · General Information About Langerhans Cell Histiocytosis (LCH) Histiocytic diseases in children and adults are caused by an abnormal accumulation of cells of the mononuclear phagocytic system. This summary discusses only Langerhans cell histiocytosis (LCH), a myeloid-derived dendritic cell disorder.
Origin, homeostasis and function of Langerhans cells and other …
WEBLangerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin. Langerin is a lectin that serves as a valuable marker for LCs in mice and...
Langerhans Cell Histiocytosis—Patient Version - NCI
WEBLangerhans cell histiocytosis is a rare blood cancer that forms when a type of white blood cell called Langerhans cells becomes abnormal and grows in different parts of the body. LCH is most common in young children but can occur at any age. Start here to find information on Langerhans cell histiocytosis treatment.
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