Lipoxygenase - Wikipedia
WebLipoxygenases ( EC 1.13.11.-) ( LOX) are a family of (non- heme) iron -containing enzymes, more specifically oxidative enzymes, most of which catalyze the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene into cell signaling agents that serve diverse roles as autocrine signals that regulate the function ...
The role of lipoxygenases in pathophysiology; new insights and …
WebAug 7, 2015 · Abstract. Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid. LOX enzymes are expressed in immune, epithelial, and tumor cells that display a variety of physiological functions, including inflammation, skin …
Lipoxygenase - an overview | ScienceDirect Topics
WebJan 13, 2011 · Lipoxygenase. Lipoxygenases are iron-containing oxidoreductase enzymes that catalyze the deoxygenation of polyunsaturated fatty acids containing a cis, cis-1,4-pentadiene-conjugated double bond system such as linoleate and linolenate to yield hydroperoxides. From: Trends in Food Science & Technology, 2020
Lipoxygenase - an overview | ScienceDirect Topics
WebLipoxygenase. Lipoxygenases are enzymes that produce fatty acid hydroxyperoxides by introducing oxygen at different positions along the carbon chain of fatty acids, mainly AA, to form the 5(S)-, 12(S)-, and 15(S)-hydroxyperoxides. From: …
Plant Lipoxygenases and Their Role in Plant Physiology
WebMar 13, 2020 · Lipoxygenases are a ubiquitous family of non-heme iron enzymes widely distributed in plants, initiate hydroperoxidation of polyunsaturated fatty acids containing cis, cis -1,4-pentadiene moieties, and produce phytooxylipins.
Regulation and Functions of 15-Lipoxygenases in Human Macrophages
WebJul 4, 2019 · Lipoxygenases (LOXs) are non-heme iron-containing dioxygenases that catalyze the stereo-specific peroxidation of polyunsaturated fatty acids (PUFAs) containing one or more 1,4- cis, cis pentadiene moieties to the corresponding hydroperoxy derivatives ( Kuhn et al., 2018 ).
Lipoxygenases and their involvement in programmed cell death
WebJul 24, 2001 · Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and the synthesis of signaling molecules. Consequently, they induce...
Lipoxygenase - an overview | ScienceDirect Topics
WebLOX exists in a broad range of organisms, including prokaryotes (Cyanobacteria and Proteobacteria), unicellular protista (red and green algae), fungi, plants (mosses and flowering plants), and animals from the basal placozoan Trichoplax to primates ( Ivanov et al., 2010; Horn et al., 2015 ).
Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition …
WebThe Lipoxygenase Superfamily. Occurrence. Lipoxygenases are found widely in plants, fungi, and animals ( 1. , 2. , 3. , 4. , 5. ). The suitable substrates are polyunsaturated fatty acids containing a series of cis double bonds. These are the essential fatty acids in humans.
Lipoxygenases: occurrence, functions and catalysis - PubMed
WebLipoxygenase. Lipid peroxidation is common to all biological systems, both appearing in developmentally and environmentally regulated processes. Products are hydroperoxy polyunsaturated fatty acids and metabolites derived there from collectively named oxylipins. They may either originate from chemical oxidation o ….
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