Peroral administration is the predominantly acceptable route of drug administration owing to its benefits such as self administration with minimal discomfort to patients, which improves patient compliance, makes it cost effective and provides flexibility

Esophageal achalasia is a motility disorder characterized by incomplete or absent lower esophageal sphincter (LES) relaxation and uncoordinated or absent esophageal peristalsis resulting in dysphagia, regurgitation, retrosternal pain, and weight loss.