Phosphonate - Wikipedia
WEBMany commercially important compounds are phosphonates, including glyphosate (the active molecule of the herbicide Roundup ), and ethephon, a widely used plant growth regulator. Bisphosphonates are popular drugs for treatment of osteoporosis. [1] Clodronic acid is a bisphosphonate used as a drug to treat osteoporosis.
Understanding the Phosphonate Products - Penn State Extension
WEBJan 1, 2023 · In the broadest sense, the term phosphonate describes any compound containing a carbon to phosphorus bond. Some examples of phosphonate compounds include organophosphate insecticides, antiviral medicines, flame retardants, and …
phosphonates - What are phosphonates?
WEBPhosphonates (or phosphonic acids) are a broad family of organic molecules based on phosphorus (chemical symbol P), carbon (C), oxygen (O) and hydrogen (H). A variety of phosphonates (including many amino phosphonates) occur naturally and in many different types of organisms. The metabolic functions of phosphonates in organisms include cell ...
Phosphonates: Their Natural Occurrence and Physiological Role
WEBFeb 20, 2019 · Phosphonates are organophosphorus compounds characterized by a stable carbon-to-phosphorus (C—P) bond, which usually resists biochemical, thermal, and photochemical decomposition. The first phosphonate (compound 1, Figure 1), being an analog of β-alanine and taurine, was isolated in 1959 …
Phosphonates, their complexes and bio-applications: A …
WEBJan 1, 2012 · Specific interactions with various metal ions will be discussed in the context of their biological, biomedical and nanotechnological applications. Several complexes will be shown to reveal a spectacular spectrum of possibilities, which the phosphonate moiety gives to coordination chemistry.
Organophosphonates revealed: new insights into the microbial …
WEBApr 29, 2013 · Key Points. Organophosphonates are ancient molecules that predate phosphates as the most abundant form of P in the biosphere. They contain the chemically stable C–P bond. Synthetic...
Global and seasonal variation of marine phosphonate metabolism
WEBJun 23, 2022 · This study is the most comprehensive metagenomic survey of marine microbial phosphonate cycling to date and provides curated databases for 14 genes involved in phosphonate cycling.
Phosphonate Biochemistry | Chemical Reviews - ACS Publications
WEBOct 27, 2016 · This review is a comprehensive summary of the occurrence and function of organophosphonic acids natural products along with the mechanisms of the enzymes that synthesize and catabolize these molecules.
Phosphonates and Phosphonate Prodrugs in Medicinal …
WEBMay 20, 2022 · Phosphonates are compounds bearing a phosphonate (P (O) (OH) 2) group attached to the molecule via a P-C bond. They serve as non-hydrolyzable phosphate mimics in various biomedical applications. Usually, they inhibit enzymes utilizing phosphates as substrates.
Phosphonate - an overview | ScienceDirect Topics
WEBAlthough phosphonate natural products have been known for more than half a century, the past decade has seen a renewed interest in the genetics, biochemistry, and structural biology (Nair & van der Donk, 2011) of their biosynthesis. Genome mining experiments, based on using the PEP mutase and PnPy decarboxylase genes …
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