Reperfusion injury - Wikipedia
WEBReperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
Pathophysiology of Reperfusion Injury - Mechanisms of …
WEBReperfusion injury is a multi-factorial process resulting in extensive tissue destruction. The aim of this review is to summarise these molecular and cellular mechanisms and thus provide an insight into possible windows for effective therapeutic intervention.
Vascular Reperfusion Injury - StatPearls - NCBI Bookshelf
WEBAug 14, 2023 · Once reperfusion injury has occurred, it can present as acute heart failure, cerebral dysfunction, SIRS (systemic inflammatory response system), and multi-organ failure. The most common presentation of reperfusion in the heart is ventricular arrhythmias, myocardial wall rupture, microvasculature abnormalities, and myocyte death.
Reperfusion therapy - Wikipedia
WEBReperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). Reperfusion therapy includes drugs and surgery. The drugs are thrombolytics and fibrinolytics used in a process called thrombolysis.
Approach to reperfusion therapy for acute ischemic stroke
WEBOct 17, 2023 · REPERFUSION THERAPIES. The immediate goal of reperfusion therapy for acute ischemic stroke is to restore blood flow to the regions of brain that are ischemic but not yet infarcted. The long-term goal is to improve outcome by reducing stroke-related disability and mortality.
Reperfusion injury of the heart - UpToDate
WEBNov 14, 2023 · Myocardial injury in the setting of an acute myocardial infarction (MI) is the result of ischemic and reperfusion injury. Reperfusion therapies, including primary percutaneous coronary intervention and fibrinolytic therapy, promptly restore blood flow to ischemic myocardium and limit infarct size.
Stroke Reperfusion Injury - StatPearls - NCBI Bookshelf
WEBOct 31, 2022 · Go to: Due to the lack of worldwide assessment data on acute ischemic stroke (AIS) reperfusion injury after thrombolysis and mechanical thrombectomy, it is hard to predict the epidemiology of I/R injury. However, the term hemorrhagic transformation (HT) can be considered an expression of reperfusion injury.
Reperfusion Therapies for Acute Ischemic Stroke | Stroke
WEBDec 16, 2010 · Arterial recanalization and subsequent reperfusion have extensively demonstrated their ability to restore brain function when performed shortly after acute ischemic stroke. 1 However, arterial recanalization does not …
Myocardial Reperfusion Injury | New England Journal of Medicine
WEBSep 13, 2007 · The potentially detrimental aspect of myocardial reperfusion injury, termed lethal reperfusion injury, is defined as myocardial injury caused by the restoration of coronary blood flow after an...
Acute Myocardial Infarction: Enhancing the Results of Reperfusion …
WEBReperfusion therapy with thrombolytic agents (or immediate angioplasty) is the mainstay of treatment of acute myocardial infarction. Critical components of the initial assessment of the patient with acute infarction are determination of candidacy for thrombolytic therapy and improved efficiency in its timely administration.
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