Roxarsone - Wikipedia
WEBRoxarsone is an organoarsenic compound that has been used in poultry production as a feed additive to increase weight gain and improve feed efficiency, and as a coccidiostat. As of June 2011, it was approved for chicken feed in the United States, Canada, Australia, and 12 other countries.
Roxarsone: Uses, Interactions, Mechanism of Action | DrugBank …
WEBFeb 25, 2016 · Roxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of coccidian parasites. The drug is also approved in the United States for use in pigs. Type. Small Molecule. Groups. Vet approved. Structure. Download. …
Organoarsenic Drugs over Time: The Pharmacokinetics of Roxarsone …
WEBAug 1, 2016 · In this issue of EHP, researchers determined the levels of arsenic metabolites present in chicken breast after feeding the birds an arsenic-based animal drug called roxarsone. 3 There are many different species (chemical forms) of arsenic, some more toxic than others.
Roxarsone - an overview | ScienceDirect Topics
WEBRoxarsone. roxarsone [rok-sahr′sōn] an organic arsenical compound used as a growth promotant and coccidiostat in swine and poultry. From: Saunders Comprehensive Veterinary Dictionary (Fifth Edition), 2021. Related terms: Arsenical; Dermatitis; Hernia; Cat; Dog; Mouse; Rat; Pig; Sheep; Ruminant
Roxarsone Promotes Glycolysis and Angiogenesis by Inducing …
WEBApr 4, 2021 · Roxarsone (Rox) is an organic arsenic compound used as a feed additive to promote animal growth. The release of Rox into the environment poses risks to human health. Rox demonstrated tumor-promoting and proangiogenic effects in xenograft models.
Roxarsone, Inorganic Arsenic, and Other Arsenic Species in …
WEBMay 11, 2013 · Background: Inorganic arsenic (iAs) causes cancer and possibly other adverse health outcomes. Arsenic-based drugs are permitted in poultry production; however, the contribution of chicken consumption to iAs intake is unknown.
Roxarsone | C6H6AsNO6 | CID 5104 - PubChem
WEBRoxarsone is an organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl. It has a role as a coccidiostat, an antibacterial drug, an agrochemical and an animal growth promotant. It is an organoarsonic acid and a member of 2-nitrophenols. It is functionally related to a phenylarsonic acid.
Efficient Degradation of Organoarsenic by UV/Chlorine Treatment ...
WEBRoxarsone (ROX) has been widely used as an organoarsenic additive in animal feeding operations and poses a risk to the environment. Here, we first report the efficient degradation of ROX by UV/chlorine, where the kinetics, removal of total arsenic (As), and cytotoxicity were investigated.
The role of organic and inorganic substituents of roxarsone …
WEBJul 1, 2023 · Roxarsone (3-nitro-4-hydroxyphenylarsonic acid, ROX) is one of the most commonly used phenylarsonic feed additives that has been extensively applied in the centralization-breeding industry (swine and poultry) for parasite control, stimulating rapid growth, and meat pigmentation ( Joshi et al., 2017; Xie and Cheng, 2021 ).
Environmental Behavior and Remediation Methods of Roxarsone
WEBJul 28, 2022 · Roxarsone (ROX) is used extensively in the broiler chicken industry, and most is excreted in poultry litter. ROX degradation produces inorganic arsenic, which causes arsenic contamination of soil and aquatic environment. Furthermore, elevated arsenic concentrations are found in livers of chickens fed ROX.
Organoarsenic Roxarsone Promotes Angiogenesis In Vivo
WEBOct 9, 2015 · Roxarsone, an organoarsenic feed additive, is widely used worldwide to promote animal growth. It has been found to exhibit a higher angiogenic index than As III at lower concentrations and to promote angiogenic …
Interaction between roxarsone, an organic arsenic ... - ScienceDirect
WEBOct 1, 2023 · Roxarsone (RX) is an arsenic (V) organic compound used to treat parasitic diseases and as an additive for animal fattening. When the animal excretes RX, the residues may lead to environmental contamination.
Applied Sciences | Free Full-Text | Comparative Study of Roxarsone ...
WEBFeb 10, 2022 · Roxarsone, an organoarsenic compound, has been used extensively as an additive in poultry feed to promote animal growth. Although roxarsone is moderately toxic, it can be converted into more toxic compounds upon exposure to the environment, resulting in human health risks.
Roxarsone and its metabolites in chicken manure significantly …
WEBAbstract. Roxarsone is an organoarsenic feed additive which can be finally degraded to other higher toxic metabolites after excreted by animal. In this work, the uptake of As species by vegetables treated with chicken manure bearing roxarsone and its metabolites was investigated.
Roxarsone induces angiogenesis via PI3K/Akt signaling - PMC
WEBSep 28, 2016 · 3-Nitro-4-hydroxy phenyl arsenic acid, also known as roxarsone, is widely used as an organic arsenic feed additive for livestock and poultry. Only a small amount of roxarsone that in ingested in animals is absorbed by the body, which means that the vast majority of roxarsone is excreted via the feces [ 1, 2 ].
Roxarsone - an overview | ScienceDirect Topics
WEBRoxarsone. For example, Roxarsone (4-hydroxy-3-nitrophenylarsonic acid) is fed to half a billion chickens each year in Maryland alone to control coccidial intestinal parasites and is excreted unaltered. From: Encyclopedia of Microbiology (Third Edition), 2009. Related terms: Herbicide; Arsanilic Acid; Arsenical; Toxic Injury; Arsenite; Food ...
Roxarsone, Inorganic Arsenic, and Other Arsenic Species in …
WEBMay 11, 2013 · Roxarsone (3-nitro-4-hydroxyphenylarsonic acid) was approved in 1944 by the U.S. Food and Drug Administration (FDA) to treat coccidiosis (a common parasitic disease in poultry), to improve feed conversion (which allows poultry to gain weight faster), and to improve meat pigmentation (Silbergeld and Nachman 2008).
Photodegradation of roxarsone in the aquatic environment
WEBRoxarsone (ROX), an organoarsenic feed additive, can be discharged into aquatic environment and photodegraded into more toxic inorganic arsenics. However, the photodegradation behavior of ROX in aquatic environment is still unclear.
WEBRoxarsone in Natural Water Systems. Organic arsenic compounds are extensively added to the feed of broiler chickens. The most commonly used arsenic compound is roxarsone (3-nitro-4-hydroxyphenylarsonic acid), which is fed to poultry to control coccidial intestinal parasites, thereby improving feed efficiency.
Roxarsone - an overview | ScienceDirect Topics
WEBRoxarsone. For example, Roxarsone (4-hydroxy-3-nitrophenylarsonic acid) is fed to half a billion chickens each year in Maryland alone to control coccidial intestinal parasites and is excreted unaltered. From: Encyclopedia of Microbiology (Third Edition), 2009. Related terms: Disulfide Bond; Cysteine; Lysozyme; Arsanilic Acid; Methyltransferase ...
Roxarsone | Drug Information, Uses, Side Effects, Chemistry ...
WEBRoxarsone. Chemistry. Full Screen View. Also known as: 121-19-7, 4-hydroxy-3-nitrobenzenearsonic acid, 4-hydroxy-3-nitrophenylarsonic acid, 3-nitro, Ristat, Roxarson. Molecular Formula. C 6 H 6 AsNO 6. Molecular Weight. 263.04 g/mol. InChI Key. XMVJITFPVVRMHC-UHFFFAOYSA-N. FDA UNII. H5GU9YQL7L.
Biotransformation of arsenic-containing roxarsone by an aerobic …
WEBApr 1, 2019 · Roxarsone (3-nitro-4-hydroxyphenylarsonic acid, ROX) is an arsenic-containing compound widely used as a feed additive in poultry industries. ROX excreted in chicken manure can be transformed by microbes to …
Roxarsone - an overview | ScienceDirect Topics
WEBAs an example, Roxarsone is known as a coccidiostat based on organoarsenic chemicals and is widely used in poultry, turkey and pig farming to improve feed efficiency and increase bird weight [7]. Several toxic metals including As and Hg enter through the industrial environment and contaminate food.
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