Single-cell analysis - Wikipedia
WEBIn the field of cellular biology, single-cell analysis and subcellular analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level. The concept of single-cell analysis originated in the 1970s.
Single Cell Portal
WEBSingle Cell Portal. 2 New features Portal whitepaper. Reducing barriers and accelerating single-cell research. Featuring. 676 studies. 43,414,046 cells. Browse collections. Search studies Search genes. Search by filters organ species disease cell type More facets.
Single-cell sequencing techniques from individual to multiomics ...
WEBSep 15, 2020 · Here, we review single-cell sequencing techniques for individual and multiomics profiling in single cells. We mainly describe single-cell genomic, epigenomic, and transcriptomic...
Best practices for single-cell analysis across modalities
WEBMar 31, 2023 · Recent advances in single-cell technologies have enabled high-throughput molecular profiling of cells across modalities and locations. Single-cell transcriptomics data can now be...
The technological landscape and applications of single-cell multi …
WEBJun 6, 2023 · Nature Reviews Molecular Cell Biology - Single-cell multi-omics methods are essential for characterizing cell states and types. The past decade has ushered in improvements in spatial resolution...
Single-cell analysis: Advances and future perspectives - PMC
WEBMay 5, 2016 · Single-cell analysis allows the study of cell-to-cell variation within a cell population (organ, tissue, and cell culture). In order to study diseases and drug development, in-depth analysis of stem cell differentiation, cancer, physiological functions in embryos and adults can only be accomplished with single-cell analysis [ 1 - 4 ].
Current best practices in single‐cell RNA‐seq analysis: a tutorial
WEBJun 19, 2019 · Here, we detail the steps of a typical single‐cell RNA ‐seq analysis, including pre‐processing (quality control, normalization, data correction, feature selection, and dimensionality reduction) and cell‐ and gene‐level downstream analysis.
Single-cell sequencing - Wikipedia
WEBSingle-cell sequencing examines the nucleic acid sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. [1]
The single-cell sequencing: new developments and medical …
WEBJun 26, 2019 · The single-cell sequencing technologies can sequence and quantify the whole genome of germ cells and embryonic cells at the single-cell level (Fig. 2 ). This will help to understand the occurrence of germ cells and the screening, diagnosis, and treatment of reproductive and genetic diseases.
Single-Cell Genomics - PubMed
WEBBackground: Single-cell genomics is an approach to investigate cell heterogeneity and to identify new molecular features correlated with clinical outcomes. This approach allows identification of the complexity of cell diversity in a sample without the loss of information that occurs when multicellular or bulk tissue samples are analyzed.
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