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  1. Cleveland Clinic
    https://my.clevelandclinic.org/health/drugs/24914-taxane

    Taxanes for Cancer - Cleveland Clinic

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    Taxane Derivatives | DrugBank Online
    go.drugbank.com
    Taxanes for the Treatment of Metastatic Breast Cancer - PMC
    ncbi.nlm.nih.gov
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  2. Studies of taxanes
    National Center for Biotechnology Information
    A systemic review of taxanes and their side effects in metastatic breast cancer
    Taxanes-containing chemotherapy constitutes an essential backbone for both early and metastatic breast cancer (mBC). However, the two major taxane drugs—paclitaxel and docetaxel—have distinct safety profiles. In this review, we summarize the safety outcome
    Author: Jiun-I. Lai, Ta-…
    Published: 2022
    Publication: Front Onc…
    National Center for Biotechnology Information
    Taxane Toxicity - StatPearls - NCBI Bookshelf
    Taxanes are a diverse class of chemotherapeutic agents comprising paclitaxel, docetaxel, cabazitaxel, and albumin-bound paclitaxel (nab-paclitaxel), which work by stabilization of the microtubules. The resulting cell cycle inhibition during the G2/M
    Author: Uzma Ismail, …
    Published: 2023/03/12
    Affiliations: Specialist …
    PubMed
    Taxanes in cancer treatment: Activity, chemoresistance and its overcoming
    Since 1984, when paclitaxel was approved by the FDA for the treatment of advanced ovarian carcinoma, taxanes have been widely used as microtubule-targeting antitumor agents. However, their historic classification as antimitotics does not describe all
    Author: Luciana Mosca
    Published: 2021/1
    Keywords: ABC transp…
    PubMed
    Taxanes - PubMed
    The taxanes or taxoids are a closely related group of antineoplastic agents that have a unique mechanism of action as inhibitors of mitosis and which are widely used in the therapy of ovarian, breast, lung, esophageal, prostate, bladder and head and neck
    Published: 2012
    Keywords: National In…
    PubMed
    Taxanes in breast cancer: an update
    Over the past decade the taxanes have proved to be fundamental in the treatment of breast cancer. Initially found to have efficacy in metastatic breast cancer, the taxanes are now vital components in the treatment of early-stage disease, in which their
    Author: Alison K Conlin
    Published: 2007/1
    Keywords: National In…
    National Center for Biotechnology Information
    Taxanes for the Treatment of Metastatic Breast Cancer
    Taxanes have remained a cornerstone of breast cancer treatment over the past three decades, improving the lives of patients with both early- and late-stage disease. The purpose of this review is to summarize the current role of taxanes, including an
    Author: W.J. Gradishar
    Published: 2012
    Publication: Breast Ca…
    PubMed
    Taxanes: an overview of the pharmacokinetics and pharmacodynamics
    Paclitaxel and docetaxel have emerged in the last two decades as effective antitumor agents in a variety of malignancies. Paclitaxel is a semisynthetic taxane isolated from bark of the Pacific yew tree. Docetaxel is a semisynthetic taxane derived from
    Author: U Vaishampayan
    Published: 1999/12
    Keywords: National In…
  3. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592970

    A systemic review of taxanes and their side effects in …

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    Taxane-containing regimens for metastatic breast cancer
    cochrane.org
    Taxanes in Adjuvant and Neoadjuvant Therapies for …
    cancernetwork.com
    Recommended to you based on what's popular • Feedback
  4. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK589655

    Taxane Toxicity - StatPearls - NCBI Bookshelf

    WebMar 12, 2023 · Extensive toxicities, including hypersensitivity reactions, myelosuppression, and neuropathy, often limit the use of taxanes. This activity reviews the etiology, incidence, evaluation, and treatment of …

  5. WebMD
    https://www.webmd.com/breast-cancer/taxanes-breast-cancer

    How Taxanes Treat Breast Cancer - WebMD

  6. PubMed
    https://pubmed.ncbi.nlm.nih.gov/33429249

    Taxanes in cancer treatment: Activity, chemoresistance …

  7. People also ask
    What are taxanes used for?
    Taxanes are a class of chemotherapy drugs providers use to treat ovarian cancer, breast cancer and prostate cancer, among other cancer types. They prevent cell division, or mitosis, the process cancer cells use to make more cancer cells. They kill cancer cells and slow tumor growth. Taxanes include paclitaxel, docetaxel and cabazitaxel.

    Taxanes for Cancer - Cleveland Clinic

    my.clevelandclinic.org
    What are the side effects of taxanes?
    The side effects vary between different taxanes, but the common ones include myelosuppression, neuropathy, and hypersensitivity reactions. Taxanes have been known to cause (upper) gastrointestinal bleeding.

    Taxane Toxicity - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    What types of cancers can taxanes treat?
    Taxanes also treat: Bladder cancer. Cervical cancer. Gastrointestinal cancer. Head and neck cancers. Kaposi sarcoma. Lymphoma. Non-small cell lung cancer. Prostate cancer. Uterine cancer.

    Taxanes for Cancer - Cleveland Clinic

    my.clevelandclinic.org
    Do taxanes kill cancer cells?
    They prevent cell division, or mitosis, the process cancer cells use to make more cancer cells. They kill cancer cells and slow tumor growth. Taxanes include paclitaxel, docetaxel and cabazitaxel. What are taxanes?

    Taxanes for Cancer - Cleveland Clinic

    my.clevelandclinic.org
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  8. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002726

    Current Perspectives on Taxanes: Focus on Their …

  9. PubMed
    https://pubmed.ncbi.nlm.nih.gov/31644104

    Taxanes - PubMed

  10. ScienceDirect
    https://www.sciencedirect.com/topics/neuroscience/taxane

    Taxane - an overview | ScienceDirect Topics

  11. Nature
    https://www.nature.com/articles/s41420-021-00554-5

    Platinum drugs and taxanes: can we overcome resistance?

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