Metrifonate - Wikipedia
WEBMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into the active agent dichlorvos. It is used as an insecticide.
Trichlorfon Facts | Pesticides | US EPA
WEBTrichlorfon Facts. EPA has assessed the risks of trichlorfon and reached a decision presented in the "Report on FQPA Tolerance Reassessment Progress and Interim Risk Management Decision for Trichlorfon" (commonly known as a TRED) for this organophosphate (OP) pesticide.
Trichlorfon | C4H8Cl3O4P | CID 5853 - PubChem
WEBTrichlorfon is a phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical, an EC 3.1.1.8 (cholinesterase) inhibitor, an anthelminthic drug and an insecticide.
Trichlorfon - an overview | ScienceDirect Topics
WEBTrichlorfon is primarily an indirect inhibitor of AChE, that is, it is converted in the body to the active chemical inhibitor dichlorvos. In fact, trichlorfon is considered to be a slow release cholinesterase inhibitor, transformed nonenzymatically to dichlorvos.
Dichlorvos in the United States: Harmful Health Effects
WEBNaled and trichlorfon (also an organophosphate pesticide) are rapidly metabolized or degraded to dichlorvos (DDVP) in food, drinking water, and the environment. (See figure.)
WEBtrichlorfon include the control of endo- and ectoparasites in, or on, domestic animals and fish. Under the generic name of metrifonate, trichlorfon is used as an antihelminthic, and in the treatment of schistosomiasis in humans.
Trichlorfon Health and Safety Guide - Health and Safety Guide 66
WEBTrichlorfon is a colourless crystalline powder that is stable at room temperature. It is slowly hydrolysed in acid media; the half-life is 526 days at pH 1-5 and 20°C.
Trichlorfon (HSG 66, 1991) - International Programme on …
WEBINTERNATIONAL LABOUR ORGANISATION. WORLD HEALTH ORGANIZATION, GENEVA 1991. This is a companion volume to Environmental Health Criteria 132: Trichlorfon. Published by the World Health Organization for the International. Programme on Chemical Safety (a collaborative programme of the United.
Study on the acute toxicity of trichlorfon and its breakdown
WEBNov 25, 2023 · Trichlorfon, one of the most widely used organophosphate insecticides, is commonly employed in aquaculture and agriculture to combat parasitic infestations. However, its inherent instability leads to rapid decomposition into dichlorvos (DDVP), increasing its toxicity by eightfold.
Trichlorfon - World Health Organization
WEBMarketed since the 1950s, trichlorfon is used to protect field and fruit crops, to control forest insects, and to control internal and external parasites in domestic and farm animals. Trichlorfon, formulated as metrifonate, has also been used for the pharmacological treatment of Schistosoma haematobium in millions of patients.
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