Khon Kaen is the capital of Khon Kaen province and the fourth largest city in Thailand. It is one of the four major cities of Isan, Thailand, also kn…Khon Kaen is the capital of Khon Kaen province and the fourth largest city in Thailand. It is one of the four major cities of Isan, Thailand, also known as the "big four of Isan", the others being Udon Thani, Nakhon Ratchasima, and Ubon Ratchathani.
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