Loiano is a town and comune of Metropolitan City of Bologna in the Emilia-Romagna region of Italy in the Tusco-Emilian Apennines at 714 metr…Loiano is a town and comune of Metropolitan City of Bologna in the Emilia-Romagna region of Italy in the Tusco-Emilian Apennines at 714 metres above sea level. Highway SS 65 connects it to Bologna, 35 kilometres to the north, and Florence, 73 kilometres to the south.