Durham is a city in the U.S. state of North Carolina and the county seat of Durham County. Small portions of the city limits extend into Orange …Durham is a city in the U.S. state of North Carolina and the county seat of Durham County. Small portions of the city limits extend into Orange County and Wake County. With a population of 283,506 in the 2020 census, Durham is the 4th-most populous city in North Carolina, and the 71st-most populous city in the United States. The city is located in the east-central part of the Piedmont region along the Eno River. Durham is the core of the four-county Durham-Chapel Hill, NC Metropolitan Statistical Area, which had an estimated population of 608,879 in 2023. The Office of Management and Budget also includes Durham as a part of the Raleigh-Durham-Cary, NC Combined Statistical Area, commonly known as the Research Triangle, which had an estimated population of 2,368,947 in 2023.
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