Iztapalapa is a borough in Mexico City, located on the east side of the entity. The borough is named after and centered on the formerly inde…Iztapalapa is a borough in Mexico City, located on the east side of the entity. The borough is named after and centered on the formerly independent municipality of Iztapalapa, which is officially called Iztapalapa de Cuitláhuac for disambiguation purposes. The rest is made up of a number of other communities which are governed by the city of Iztapalapa.