Littlefield is a city in and the county seat of Lamb County, Texas, United States. Its population was 6,372 at the 2010 census. It is located in a …Littlefield is a city in and the county seat of Lamb County, Texas, United States. Its population was 6,372 at the 2010 census. It is located in a significant cotton-growing region, northwest of Lubbock on the Llano Estacado just south of the Texas Panhandle. Littlefield had a large denim-manufacturing plant operated by American Cotton Growers.
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