Mesquite is a city in the U.S. state of Texas, located in Dallas County with portions extending into Kaufman County. In 2020, its population was …Mesquite is a city in the U.S. state of Texas, located in Dallas County with portions extending into Kaufman County. In 2020, its population was 150,108 making it the 21st-most populous city in Texas. Mesquite is positioned at the crossroads of four major highways, making locations such as downtown Dallas, Lake Ray Hubbard, Dallas Love Field, and DFW International Airport accessible.
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