These properties led Lee and colleagues to investigate cadherin molecule functioning in synovial lining and in autoimmune arthritis. Initial investigations in healthy mice demonstrated that ...

Ling Xiao Liu and colleagues now report that cadherin-17 (CDH17), which encodes a cell surface adhesion molecule not found in healthy adult liver, is a novel oncogene in HCC and is an attractive ...

Tumour-free testes exhibit strong cytoplasmatic expression of N-cadherin in all spermatogenesis and Sertoli cells (28/28) (IRS 10.52 ±1.96) (Figure 1A). Cells of the interstitium and Leydig cells ...

TORL-3-600 is an ADC that targets the cadherin 17 (CDH17) protein, which plays a role in cell-to-cell adhesion. It is currently in Phase I trial (NCT05948826) as a treatment for CDH17-positive ...

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

Scientists from Universidad Carlos III de Madrid (UC3M) and Johns Hopkins University (JHU), in the U.S., have analyzed the growth of breast tumors from a biomechanical perspective and have created a ...

Most importantly, they found that the cells abundantly expressed adhesive proteins such as connexin 43 and N-cadherin, which would promote their vascular integration into an existing heart.

The second DMC review recommends the continuation of dose escalation in the clinical trial as per protocol. The interim ...

Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process.

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.