an overview of glycosyltransferases and glycosidases, the biological roles of glycans, and a genome-wide view of the many sequences that appear to code for proteins that make, break and bind ...

Instead, they are built from simple building blocks by molecular machines called glycosyltransferases. When glycosyltransferases are dysfunctional, this can have drastic consequences and facilitate ...

A major focus of our work is on POGLUT1 and other glycosyltransferases responsible for the addition of O-linked glycans to epidermal growth factor-like (EGF) repeats. Specifically, we would like to ...

And there are benefits of plant cell expression systems, notably their impact on the cost of goods sold (COGS).

Clausen H., Gahlay G. K., Jarvis D. L., Johnson R. W., Moniz H. A., and Moremen K. “The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a ...

Specifically, his work has demonstrated that glucose dysregulation impacts glycosylation and glycosyltransferases that drive cell proliferation in idiopathic pulmonary arterial hypertension (IPAH).