By examining haplotypes, scientists can identify patterns of genetic variation that are associated with health and disease states. For instance, if a haplotype is associated with a certain disease ...

APOE4 gene is strongly associated with the disease and new study says the link may be stronger than previously thought.

Most of the Cohen modal haplotypes that we observe are carried by individuals of the Buba clan which, in Lemba oral tradition, had a leadership role in bringing the Lemba out of Israel." ...

This includes which allele (if either) is fixed; the allele and gene copy fixation times; the final frequencies of alleles, haplotypes, and genotypes; and the ancestral (generation 0) haplotypes ...

These findings indicate that APOE4 homozygotes not only have a higher risk but also develop Alzheimer’s earlier than those ...

Genetic bottlenecks therefore lead to an increase in homozygosity, which takes place when identical haplotypes are inherited ...

How can you identify which technique is best suited to your research requirements? In this article, we explore the advantages of qPCR and dPCR, considering specific applications and deliverable ...

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease ...

** I expect you to read: Avise, J.C. 2004. Chapter 7: Speciation and hybridization. In Molecular Markers, Natural History and Evolution (2nd edn.). Chapman and Hall, New York. Having at least briefly ...

Le gène APOE4 est connu depuis de nombreuses années comme un facteur de risque génétique de la maladie d’Alzheimer (MA) sporadique et est également impliqué dans d’autres pathologies telles que l’athé ...