Scientists have discovered how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose based epigenetic modification.

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so ...

Thirty-two patients with renal disease were treated with immunosuppressive therapy between September, 1963, and September, 1965. Of these, 4 were treated for less than fourteen days and are ...

There couldn’t be enough ways to show your love for your pet dog, including kissing them on them. I do it, too, just like my ...

Corticosteroids are used in pharmacologic doses for their anti-inflammatory and immunosuppressive properties. When corticosteroids are used for these purposes, the systemic agents with the least ...

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma ...

Purpose. Induction immunosuppressive therapies for patients undergoing renal transplantation are reviewed. Summary. The goal of induction therapy is to prevent acute rejection during the early ...

In a study published in Science on May 3, researchers unveiled two responding patterns of tumor-infiltrating B cells with ...

Mupadolimab is designed to react with a region of the molecule that acts to stimulate B cells and block production of ...

FILSPARI (sparsentan) is a once-daily, oral medication designed to selectively target two critical pathways in the disease progression of IgAN (endothelin-1 and angiotensin II) and is the first and ...

Wistar’s Veglia lab identified how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose ...

Until now, it has been poorly understood how monocyte-derived macrophages and microglia create an immunosuppressive tumor microenvironment in glioblastoma. The Veglia lab investigated the cellular ...