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The primary protein in cartilage, Type II Collagen (CII) is crucial to joint health and function. Yet, the involvement of CII in the process of joint inflammation has proven difficult to substantiate.

Collagen is a protein that aids in strengthening skin, bone and other tissues. There are at least 16 different types of collagen, and 80% to 90% of collagen in the body is types I, II or III [1].