However, 71% of participants did have a lengthening of their PSA doubling time (PSADT). PSADT is the amount of time it takes ...

The authors' approach has been to use PSADT less than 3 years (20% of patients) or grade progression to Gleason 4+3 or higher (5%). The authors used the GLMM method based on ln(PSA) to calculate ...

We developed tables to predict the risk of positive bone scans by PSA and PSADT. Combining PSA levels and kinetics may help select patients with CRPC for bone scans.

J Natl Compr Canc Netw. 2007;5(7):693-698. The primary concern with using PSADT as a trigger for curative intervention is that it may act as a marker of aggressive disease that has already ...