Purpose: A review of the significant findings related to the use of the thiazolidinediones (TZDs) in the treatment of patients with type 2 diabetes mellitus and heart failure was conducted.

T hiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease. While TZDs were extremely ...

The FDA took many TZDs off the market and drugs like Metformin replaced medicines to treat diabetes, but Olefsky and his team didn’t forget about the older drugs. “If you go back to when they ...

Thiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease. While TZDs were extremely popular in ...

Although these results are intriguing and certainly provide evidence for a subpopulation of NASH patients that do not appear to respond to therapy with the TZDs, this study is limited by the ...

Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690 ...

Renal or hepatic impairment. Elderly. Pregnancy. Nursing mothers. Concomitant thiazolidinediones (TZDs) may cause fluid retention and heart failure; consider dose reduction or discontinue TZDs.

Researchers have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives. Thiazolidinediones (TZDs) are a class of drug that ...

Thiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease. While TZDs were extremely popular ...