Beqvez is a one-time AAV-based gene therapy designed to introduce in the transduced cells a functional copy of the factor IX ...

Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved BEQVEZ™ (fidanacogene ...

The Producer service offers customers a second option for accessing Asimov's technology for the cell and gene therapy ...

The personalised treatment, Tecartus also known as autologous anti-CD19-transduced CD3+, is a CAR-T therapy which uses the patient’s white blood cells which are then reengineered in a laboratory so ...

Ahead of the FDA’s June target action date for Sarepta’s Duchenne muscular dystrophy gene therapy, ICER Chief Medical Officer David Rind blasted the regulator’s accelerated pathway in a JAMA viewpoint ...

German biotech Immatics has two major data readouts due 2H24, and a pivotal study initiation in melanoma - the risk reward is ...

Pfizer Inc. has announced that the U.S. Food and Drug Administration (FDA) has approved BEQVEZ (fidanacogene elaparvovec-dzkt ...

4b,c). The control virus transduced approximately 45% of BLPs and treatment with TGF-β1 led to a 5.3-fold induction of Id3. Approximately 75% of BLPs in the Smad7 virus–transduced population ...

Figure 1: Reconstitution of hematopoiesis with GFP-expressing peripheral-blood cell progeny in lethally irradiated mice after transplantation of GFP-transduced BM. Figure 2: Engraftment of BM ...

An in vitro screening process ensures that only those cells that have successfully been transduced or transfected by the ...

Protocol 2498: Phase I/II Study of Adoptive Immunotherapy with Virus Specific CD8+ T Cells that have been Transduced to Express a WT1-Specific T Cell Receptor for Patients with High Risk or Relapsed ...

Across all runs, killing by the nsIL3-33mb15 construct against healthy CD34+ HPCs was below that of un-transduced control gamma-delta T cells. “INB-300 can selectively target leukemia cells ...