Discover how Denali Therapeutics Inc's patented method generates polypeptides targeting transferrin receptor-expressing cells, crossing the blood-brain barrier with enhanced brain uptake. Explore the ...

We previously reported a patient with hereditary hypotransferrinemia who suffered from severe anemia and growth retardation and was diagnosed on the basis of an extremely low level of serum ...

The statement on transferrin saturation (TSAT): “Iron deficiency is present if the TSAT is less than 20%, …” (1) is not correct. Only 0.07% of the total body iron (approximately 0.0035 g of ...

In a study of 11,302 patients starting peritoneal dialysis in the United States, those who had a transferrin saturation (TSAT) of 20% or less had a 30.2% increased risk for early mortality compared ...

In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in ...

msm1.ukl.uni-freiburg.de Background: Soluble transferrin receptor (sTfr) is a new marker of iron status and erythropoietic activity. It has been included in multivariable blood testing models for the ...

Clathrin-mediated endocytosis is a major endocytic route used by transferrin, growth-factor receptors and pathogenic viruses during infectious entry. Although clathrin-dependent uptake is the best ...

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes ...

These atoms that have been lost from the chemical groups that hold them will not always be safely returned to some structure like transferrin or haemoferritin. Some of them will react with water and ...

Reduce DMPK expression in muscle cells with Dyne Therapeutics' patented method using an anti-transferrin receptor antibody linked to an oligonucleotide. Learn more about this potential treatment for ...

Related Content Among the study’s limitations, the investigators were not able to adjust for comorbidity severity, transferrin saturation, or C-reactive protein levels. Disclosure: This research was ...

Former VCU guard Max Shulga has committed to Kyle Neptune and Villanova, a source told On3. The 6-foot-4 senior from Ukraine averaged 14.0 points, 4.6 rebounds, and 3.6 assists per game this past ...