Alcohol use disorder (AUD) is a global health problem with limited therapeutic options. The biochemical mechanisms that lead to alcohol addiction are not yet fully understood, and in this respect, ...
XORTX Therapeutics Inc. ("XORTX" or the “Company”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANUA WKN: A3UNZ), a late-stage ...
Mitidieri, E., Affonso, O. R., Ribeiro, L. P., and Villela, G. G., Nature, 178, 492 (1956). PHYLLIS SAVERANCE: Predoctoral trainee supported in part by a training ...
Xanthine oxidoreductase (XOR) is the enzyme responsible for the final step in purine degradation resulting in the generation of uric acid. Here we have generated mice deficient in XOR. As expected, ...