This revealed a chemical modification, known as acetylation, which only occurs when the GR is bound to cortisol. However, this acetylation does not change the function of GR as a transcription ...

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought.

Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, ...

Epigenetic modifications, such as histone acetylation and DNA methylation, serve as molecular switches, toggling genes on or ...

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex ...

That is, transcriptional activation was associated with methylation at K4, which paralleled acetylation of K9 and K14, while transcriptionally inactive chromatin was associated with K9 methylation.

For example, one group of researchers used antibody-based immunoprecipitation studies to determine that acetylation of histone H3 and methylation at lysine residue K4 appeared to coincide with ...

Weissman wrote his master’s thesis on acetylation of DNA, part of the process of gene regulation, before going on to earn an MD/PhD in immunology/microbiology at Boston University. Arriving at Penn in ...

Medical grade diamorphine is used as a pure hydrochloride salt which is distinguished from black tar heroin, a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), ...

But other insights were tissue-specific. To their surprise, Carr's team found an increase in acetylation of mitochondrial proteins involved in energy production, and in a phosphorylation signal that ...