It’s not often that one of those substances is not just a friend, but a foe. But the hormone adrenomedullin — which regulates blood pressure and supports the growth of pancreatic cancer — is both.
Enibarcimab (formerly adrecizumab) is a first-in-class non-neutralizing monoclonal antibody that binds to adrenomedullin (ADM), a vasoprotective hormone. It is believed that modulating the ADM ...
Studies in cells showed that mutated CLR failed to reach the cell surface, thus preventing the receptor’s ligand, adrenomedullin, from binding and disrupting normal adrenomedullin-CLR signalling.
Research on the vasodilating peptide hormone adrenomedullin and the herbal medicine indigo naturalis shows that they are both effective at reducing the severity of ulcerative colitis in mouse ...
Water and sodium retention during severe hypothyroidism create a state of volume depletion, low extracellular fluid osmolality and increased water retention. The hypothyroid population is ...
Eight plasma proteins including adrenomedullin (AM), interleukin 6 (IL-6), growth differentiation factor 15 (GDF15), ...
Enibarcimab (formerly adrecizumab) is a first-in-class non-neutralizing monoclonal antibody that binds to adrenomedullin (ADM), a vasoprotective hormone. It is believed that modulating the ADM pathway ...