In this Opinion article, we focus on the role of one such effector molecule, annexin A1, and summarize the recent studies that provide insight into its molecular and pharmacological functions in ...

Researchers said the technique has the ... Targeting Annexin-A1 Can Halt Cancer Cell Growth Jan. 19, 2024 — A new study highlights the effectiveness of MDX-124, the first therapeutic drug to ...

Topics comprise Agarose Gel Electrophoresis, Annexin V Binding/Propidium Iodide Uptake Assay, Tests for Sodium Radical and ...

Compared with participants who did not lose weight, recent ... Targeting Annexin-A1 Can Halt Cancer Cell Growth Jan. 19, 2024 — A new study highlights the effectiveness of MDX-124, the first ...

No Ride for Lysosomes. In wild-type i3 neurons (left), LAMP1+ lysosomes (white) are found in dendrites, soma, and axons. Without BORC5 (middle) or BORC7 (right), few lysosomes travel into axons.

Cleavage of Caspase 3, PARP1 and HSP90, as well as increased Annexin V positivity, suggest potent activation of apoptosis by this two-drug combination; increased levels of γ-H2AX, P-CHK1 (S317 ...

Our lab discovered that glucocorticoids can release a protein (called Annexin A1) from some cell types and that this mediates many of the acute effects of these hormone-drugs including their ...