In both pathways, effector caspases are finally activated that cleave and degrade cell structures, resulting in the release of apoptotic products into the circulation. New diagnostic tests can ...

Antiproliferative and apoptotic responses to TGF-β in epithelial, endothelial, neuronal and haematopoietic cells effectively limit the growth of these cell lineages. The importance of TGF-β as a ...

Research explains why some viruses present in bodily fluids don't spread through those fluids, revealing a novel defense ...

A study has found that a cannabis extract can have a "deadly" effect on a common form of cancer. Researchers from Charles ...

A research team led by Professor Haruhisa Inoue (Department of Cell Growth and Differentiation) derived iPS cells (iPSC) from ...

Mango lovers now have yet another reason to celebrate their favourite fruit. A recent study published in the journal ...

PEP-010 is a pro-apoptotic agent which has demonstrated a good safety and tolerability profile and first signals of efficacy in the CLEVer-PEPtide Phase Ia dose escalation clinical trial. The ...

More information: Elyse A. Olesinski et al, Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in ...

a member of the anti-apoptotic BCL-2 proteins, for solid tumors and hematological malignancies. Zentalis Pharmaceuticals, Inc. has licensing agreements and strategic collaborations with Recurium ...

Founder, Director; Corcept Therapeutics Inc Sean Maduck; President - Corcept Endocrinology; Corcept Therapeutics Inc William Guyer; Chief Development Officer; Corcept Therapeutics Inc Matt Kaplan; ...

Apoptotic cell death is regarded as an important pathogenetic mechanism in the major immune-mediated liver diseases, primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis.