As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...

Bosentan is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your ...

Bosentan (Tracleer ®; Actelion Pharmaceuticals Ltd, Allschwill, Switzerland) was the first of a new class of drugs - the ET receptor antagonists - initially developed to treat pulmonary arterial ...

Bosentan 32mg; dispersible tabs for oral susp; tutti frutti flavor; contains phenylalanine. Must register patient in the Tracleer REMS Program (see full labeling). Take in the AM and PM.

This leaflet answers some common questions about BOSENTAN VIATRIS. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

The FDA approved a new treatment for uncontrolled high blood pressure. The once-daily oral medication, called Tryvio (aprocitentan), is expected to be available in the second half of 2024.

Nursing mothers: not recommended. Elevated liver enzymes with concomitant bosentan (see Contraindications). Increased risk of hypoglycemia with concomitant alcohol or other hypoglycemics.

Endothelin-1 is one such target. Bosentan is a nonselective endothelin antagonist approved in the USA and Europe for the treatment of pulmonary arterial hypertension and the reduction of the ...