Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Broad spectrum carbapenems were the most commonly used therapy for targeted treatment of extended-spectrum ...

Resistance to this group of antibiotics poses a significant threat to successful treatment. Carbapenems: These powerful drugs are considered a "last resort" antibiotic. Doctors reserve them for ...

Resistance to carbapenems in Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacteriaceae, mainly determined by the production of carbapenem-hydrolyzing β-lactamases, has emerged ...

Carbapenem-resistant Enterobacterales (CREs) are resistant to commonly prescribed antibiotics called carbapenems, which are considered the drugs of last resort for treating severe infections.

The incidence of extended-spectrum β-lactamase-producing Enterobacterales infections has increased substantially in recent years, now accounting for approximately 15% of isolates causing infections.1 ...

After India lost its dominance in making penicillin, a drought of three decades is coming to an end. The drug – which forms ...

Pfizer's novel combination antibiotic Emblaveo (aztreonam-avibactam) will be an option for infections that have limited ...

The team also looked at bacteria resistant to carbapenems — often considered the last line of antibiotic defense used when other antibiotics fail. In Portugal, 3 cats and 21 dogs harbored ...

Researchers also detected dogs containing bacteria resistant to carbapenems, which are part of the last line of defense in human medicine when other antibiotics have failed. Ultimately ...

OXA-181 is an enzyme that confers resistance to carbapenems. Three cats and 21 dogs (24/43 pets, 55.8%) and 28 owners (28/78 owners, 35.9%) harboured ESBL/Amp-C producing Enterobacterales.

The emergence of resistant to carbapenems Gram-negative bacteria (CR GNB) has severely challenged antimicrobial therapy. Many CR GNB isolates are only susceptible to polymyxins; however ...