New research has identified the Rho GTPase target ROCK-I as being cleaved by caspases during apoptosis. ROCK-I is known to stimulate actomyosin-based contractility. Once cleaved, ROCK-I is ...

In the later stages of viral infection, proteins called caspases are activated, and this type of protein is chiefly responsible for triggering cell death. "RNA silencing and interferon signaling ...

The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.

Apoptosis, the major form of programmed cell death, is executed by a subfamily of proteins known as caspases. During apoptosis, these “death executioners” are activated to attack a variety of cellular ...

Written by: Julian Chavarriaga, MD - Society of Urologic Oncology (SUO) Clinical Fellow at The University of Toronto, ...

Survivin: IAPs suppress host cell death in response to viral infection. By binding to caspases, they directly inhibit apoptosis. Survivin and xIAP are members of this family, differing perhaps in ...

programmed cell death, apoptosis, lace plant, Aponogeton madagascariensis, plant development, cell biology, perforation formation, caspases, ethylene, developmental ...