Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13) of all ...
Efflux Systems in Acinetobacter spp. Antimicrobial efflux is yet another important mechanism of resistance in Acinetobacter spp. In general, efflux constitutes a resistance mechanism that involves ...
Small changes in hydration determine Cephalosporinase activity of OXA-48 β-Lactamases (ACS Catalysis 2020) Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational ...