Similar to the mouse results, the researchers found that childhood or adolescent stress significantly impacted HPA axis ...

"Activation of these neurons drove T cell homing to bone marrow in a CXCR4/CXCL12 axis-dependent manner, which may be mediated by a neural circuit that stimulates corticosterone secretion.

New research is revealing potential impacts on the hormones of sea turtles affected by the Deepwater Horizon oil spill in the Gulf of Mexico.The 2010 ...

as evidenced by altered levels of corticosterone, a key hormone in stress regulation. The implications of this discovery are ...

At the same time, Belyaev found reduced levels of the stress hormone corticosterone in the domesticated foxes. Even the changes in coat color were linked to changes in the timing of development.

Despite being a first-line treatment for adolescent depression and anxiety, antidepressant drugs appear to have questionable efficacy and carry an increased risk of adverse effects in this ...

In vertebrates, an important mechanism for coping with stressors begins with adrenally-derived glucocorticoid hormones: corticosterone in amphibians, reptiles, and birds, or cortisol in fish and ...

The eyes can be used in alternation with one-week interval. The rodent subject recovers quickly as reflected in corticosterone, catecholamine and behavioural responses (van Herck et al., 2001). These ...

Future Oncol. 2015;11(1):91-106. Abiraterone was investigated in Phase I/II study in chemotherapy-naive CRPC patients: in this trial, a decline in PSA of ≥50% was observed in 67% of patients, a ...

In Germany, animal research is primarily carried out in the areas of basic research, medicine and veterinary medicine. Animal research can also be required to identify factors that pose a risk to the ...

R-335-3p, which targets FOS and inhibits its activation of NFATC1 signaling, is an important regulator for osteoclast function and responsible for the psychological stress induced osteoporosis The ...

This antagonist, which blocks the effects of elevated glucocorticoids (cortisol in humans and corticosterone in rodents), could be a novel treatment option for postpartum depression. Niwa and ...