Dublin, April 15, 2024 (GLOBE NEWSWIRE) -- The "Cyclin-Dependent Kinase 9 (CDK9) Inhibitor - Pipeline Insight, 2024" clinical trials has been added to ResearchAndMarkets.com's offering.
In the 15 March issue of Nature, Bibb et al. 1 report the use of DNA array analysis of inducible transgenic mice to identify a cyclin-dependent kinase (Cdk5) that alters striatal dopamine (D1 ...
Focusing on human cells that line breast ducts and lung tissue, scientists analysed thousands of images of single cells as ...
Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.
Marinus expects to share data from the Phase III RAISE trial of IV ganaxolone for the treatment of status epilepticus later ...
Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of ...
The anti-cancer drug abemaciclib (also known as Vernezio) has this month been added to the Australian Pharmaceutical Benefits ...
We’re also very pleased to announce our discovery program for CCNE1 (Cyclin E1), a well-validated oncology target generally considered undruggable by conventional modalities. We believe our ability to ...
The phenomenon differs according to the cyclin molecule used and is dose dependent: only a few cases have been reported with doses similar to that administered in the present case (100 mg/d).
One is a Phase-3 trial in collaboration with Duality Bio, evaluating BNT323 in patients with hormone receptor positive and ...
As part of its azenosertib clinical development program, the Company is exploring enrichment strategies targeting tumors of high genomic instability, such as Cyclin E1 positive tumors, homologous ...