More information: Zhuo Yang et al, Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager, Nature Biomedical Engineering (2024). DOI: ...

a non-classical MHC class I molecule that is expressed by various tumour cells in vivo and for which engagement with inhibitory receptors on NK cells is known to block NK-cell-mediated cytolysis.

The constant region triggers effector functions (phagocytosis, cytolysis, or initiation of complement cascade followed by cell lysis) by linking the complex to other cells of the immune system.

TNF-α is a potent inducer of the inflammatory response, a key regulator of innate immunity and plays an important role in the regulation of Th1 immune responses against intracellular bacteria and ...

Dermatology Nursing. 2005;17(1):56-59. The "Clinical Snapshot" series provides a concise examination of a clinical presentation including history, treatment, patient education, and nursing measures.